Investigating Different Coil Configurations during Magnetic Nanoparticles Hyperthermia for Prostate Cancer

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Issue Date
2023-08-28
Authors
Nour, Amro A.
Keywords
Type
Conference Presentations/Proceedings
Abstract
One of the deadliest diseases in this day and age is cancer. In order to find the best treatment, numerous researchers from various professions are working together. Magnetic nanoparticle hyperthermia is one of the therapeutic options (MNPH). In order to do this, magnetic nanoparticles (MNPs) are inserted into the tissues of cancerous tumors, and an external coil carrying current is used to produce an alternating magnetic field (AMF) that activates the MNPs inside the tumor tissues. In exchange, activation of the MNPs would provide concentrated heat at the sites of the tumors, which has the potential to be potent enough to kill tumor tissues. Eddy currents are produced at nearby healthy tissues as a result of alternating magnetic and electric fields, which is also known as a magnetic field reversal. Particularly when large currents (up to several hundred Amps) offer the necessary AMF intensity to treat deep tissue malignancies, the associated eddy currents cause unwelcome heat and harm the nearby healthy tissues. A complete computational and graphical electromagnetic examination of a genuine virtual human model is presented in this research. With various coil designs, specific absorption rates (SARs) are computed and displayed for various bodily tissues. The ideal coil arrangement with the lowest eddy currents on the surrounding healthy tissues and the highest AMF at the MNPs injected into the prostatic tumor was determined.
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